Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight

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Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight

Primary hyperparathyroidism (PHPT) is a common endocrinopathy, frequently caused by a parathyroid adenoma, rarely by a parathyroid carcinoma that lacks effective oncological treatment. As the majority of cases are present in postmenopausal women, oestrogen signalling has been implicated in the tumourigenesis. Oestrogen receptor beta 1 (ERB1) and ERB2 have been recently identified in parathyroid...

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ژورنال

عنوان ژورنال: Endocrine Connections

سال: 2015

ISSN: 2049-3614

DOI: 10.1530/ec-14-0109